Urgent Suspected Cancer: Sarcoma

NCL Wide

Before referral 

  • Review the pathway and referral criteria: Pan-London Suspected Sarcoma Referral Guide
  • Visit the London and South East Sarcoma Network for more information.
  • Use the appropriate local request form and process to arrange urgent imaging (see How to refer)
  • X-ray, ultrasound or MRI results should accompany all urgent referrals unless you suspect recurrence of previous sarcoma.
  • If the patient lives outside north central London (NCL), refer to a local imaging provider to help maintain capacity for NCL residents. 

Soft tissue sarcoma

Arrange urgent direct-access ultrasound locally.

Refer all suspected non-limb/trunk soft tissue sarcomas (intra-abdominal, retroperitoneal, head & neck, urology, breast) to University College London Hospitals (UCLH).

Refer all suspected but not highly suspicious soft tissue sarcomas of limb, trunk and abdominal wall to Wood Green CDC for an urgent direct access MRI. This referral should only be made after a local ultrasound shows abnormal findings or the report is unclear and cannot confidently confirm a benign lesion. The ultrasound report should describe the lesion as one of the following: 

  • concerning for a malignant soft tissue tumour 
  • heterogenous and vascular
  • deep to the fascia and not in keeping with a lipomatous tumour
  • an indeterminate lesion in an individual who has a condition which predisposes them to malignant soft tissue tumours (for example neurofibromatosis).

Highly suspicious, confirmed soft tissue sarcomas or recurrence of a previous sarcoma should be referred directly to the tertiary centres at either the Royal Marsden Hospital or the London Sarcoma Service (Royal National Orthopaedic Hospital/University College London Hospitals) on the urgent suspected cancer (USC) faster diagnostic standard pathway (formerly 2WW).

Soft tissue sarcoma in children

Contact paediatrician on-call urgently.

Bone sarcoma 

All suspected bone sarcomas must be referred to the Royal National Orthopaedic Hospital service only. Before referral, arrange an urgent X-ray for patients with unexplained bone swelling or tenderness not responding to analgesia or night time pain.


Eligibility Criteria

Inclusions

  • resident of north central London

Exclusions

Do not refer the following benign conditions to either Wood Green CDC or Royal Marsden or London Sarcoma Service (RNOH/UCLH):

  • subcutaneous lipomas
  • sebaceous cysts/epidermoid cyst
  • ganglions
  • giant cell tumours of the tendon sheath
  • pigmented villonodular synovitis (PVNS) of a joint
  • post-traumatic or inflammatory phenomena such as fat necrosis, abscess
  • fibromas
  • normal variant anatomy
  • lymphangiomas/haemangiomas/all vascular malformations
  • chest wall/rib asymmetry
  • tenosynovitis of the wrist (for wrist mass)
  • sternoclavicular joint degeneration
  • osteochondromas(unless suspicious of malignant degeneration)
  • indeterminate lesions of skin
  • fibrous dysplasia
  • simple bone cysts

How to Refer

EMIS form

Referral methods: e-RS

Urgent ultrasound for suspected sarcoma

Complete the Urgent Direct Access Imaging Request Form (adult and paed) – Suspected Cancer – NCL (mark as USC)

Urgent MRI for suspected sarcoma

Complete the Imaging Adult Referral Form NCL - Wood Green CDC

Where to find the forms

  • NCL Global Documents > Investigations


Referral to USC faster diagnostic standard pathway (formerly 2WW)

Complete the PAN London Suspected Sarcoma Referral fFrm and send to the Royal Marsden Hospital or the London Sarcoma Service (UCLH/RNOH).

Soft tissue sarcoma in children

Following discussion with the paediatrician on-call, complete the Pan London Suspected Children's Cancer form.

Where to find the forms

  • NCL Global Documents > Urgent Suspected Cancer (formerly 2WW)

Locations

Wood Green Community Diagnostic Centre

For suspected soft tissue sarcomas of limb, trunk and abdominal wall

University College Hospital

For suspected non-limb/trunk soft tissue sarcomas

Royal National Orthopaedic Hospital


Review date: Tuesday, 02 June 2026