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FIB-4 Calculator

NCL Wide
Age ALT AST Platelets

FIB-4 Calculator for NAFLD

NB This is only valid for non-alcoholic fatty liver disease (NAFLD) and is intended for use in conjunction with the NCL Abnormal LFT pathway. Your local guidance may differ.

Please note: The use of the FIB-4 score is not validated where a patient is over 75 years of age. Whilst the calculator will still give you a FIB-4 score, please make note of the error messages that may appear next to it.

This uses the FIB-4 formula: (age [yr]x AST [U/L]) / ((PLT [109/L]) x (√ALT [U/L]))

Calculator developed by Alex Warner.


Fibrosis stratification in NAFLD based upon:

  • FIB-4: McPherson S et al. Gut. 2010 Sep;59(9):1265-9.
  • ELF: Enhanced Liver Fibrosis Test Rosenberg et al. Gastroenterology. 2004 Dec;127(6):1704-13.
  • Combining ELF and FIB4 in NAFLD Tanwar et al. Hepatology. 2012, 56, 264A.

Alternative calculator

Review date: Saturday, 27 July 2024