The Department of Health and Social Care has issued a medicines supply notification for sodium valproate (Epilim Chronosphere®) 100mg modified release granules sachets sugar free.

The product is out of stock from late February until mid April 2026. 

Actions for prescribers

Do not initiate new patients on Epilim Chronosphere® 100mg modified release granules sachets and reserve remaining supplies for patients where there are concerns around epilepsy control being destabilised by a change in product.

ScriptSwitch® messages have been enabled to provide information to support primary care.

Clinicians should refer to the Specialist Pharmacy Service Medicines Shortage Tool MSN/2026/012 for the full supporting information and recommended actions required.